ESPE Abstracts

Objective: Linear growth is impaired in children with type 1 diabetes (T1D) and poor metabolic control. A good metabolic control is a key therapeutic goal to prevent vascular complications but also for ensuring an appropriate anthropometric development during childhood. In this study, we aimed to identify and characterize the effects of glycemic variability on linear growth in children with T1D.Methods: Data from 144 pre...

Background: DKA is the most serious life-threatening acute complication of T1D. Few data are available evaluating the possible role of anthropadiposity indexes in paediatric DKA in a selected population of prepubertal children. We aimed to identify the possible correlation between adiposity indexes and the presence and severity of DKA at T1D onset.Methods: 195 prepubertal children (84Female/111Male) diagnosed be...

A 11years-old Italian severely obese prepubertal female (BMI: 32.4 kg/m2; SDS-BMI: 2.63) was admitted to the emergency department due to worsening dyspnea and chest pain associated with severe polyuria, lethargy and lost weight from (85 kg to 78 kg in 7 days). She has history of severe hypertension treated with amlodipine and bisoprololo and a positive family history of Type 2 diabetes. At admission, she was dehydrated and lethargic, but can be awakened after painful and verba...

Background: An increased incidence of Type 1 diabetes has been observed worldwide over the past 30 years. Obesity is a well-documented risk factor for Type 2 diabetes (T2D), but poor studies have postulated an association between the obesity and overweight and the rate of T1D in these age groups. This is known as Accelerator Hypothesis. In addition, a further effect seems to be exerted COVID-19 pandemic which is related to raised rate of T1D onset and obesity....