hrp0082fc9.3 | Beta cells | ESPE2014
Simaite Deimante
, Kofent Julia
, Gong Maolian
, Ruschendorf Franz
, Jia Shiqi
, Arn Pamela
, Bentler Kristi
, Ellaway Carolyn
, Kuhnen Peter
, Hoffmann Georg
, Blau Nenad
, Spagnoli Francesca
, Hubner Norbert
, Raile Klemens
Background: Mutations in more than 20 genes are described to cause monogenic diabetes. Nevertheless, numerous families with diabetes of unknown ethology and suspected genetic defect have no molecular diagnosis. This not only impedes our understanding of disease mechanisms but also prevents from predicting the clinical course of the patients and applying the pathogenesis-oriented treatment.Objective: To identify novel gene(s), causing monogenic adolescent...