hrp0098fc6.6 | Fat, Metabolism and Obesity 1 | ESPE2024

Novel Melanocortin and Gut-peptide Dual Agonist for Obesity and Diabetes Treatment

Elfers Clinton , Chichura Kylie , Ashlaw Emily , Mullins Ginger , Chavez Miranda Isabella , Doyle Robert , Roth Christian

Background: While research demonstrated successful weight and BMI reduction in response to recent obesity drugs in adults and adolescents, there are significant limitations of current drugs targeting single receptors, such as problems maintaining a reduced weight status, and the high rates of gastrointestinal adverse events, which can lead to discontinuation of treatment. Based on this, we hypothesized that a more effective and better tolerated obesity interve...