hrp0095p2-253 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Clinical characteristic and testicular function in children with 46 XY disorder of sex development in a developing country

Khater Doaa , Raafat Shaymaa , Badawy Haytham , Omar Magdy

Disorders of sex development (DSD) comprise a heterogeneous group of conditions involving interference with normal sex differentiation and hormonal production in the embryo resulting in relatively rare conditions having diverse pathophysiology. The aim of the current work is to study the clinical characteristics and testicular function of patients with 46 XY DSD. A cross-sectional study was done included children with initial presentation of atypical genitalia and satisfied th...

hrp0092p1-413 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology (2) | ESPE2019

Assessment of the Function of Lower Urinary Tract Following Feminizing Genitoplasty in Females with Congenital Adrenal Hyperplasia

Elsayed Shaymaa , Wafa Ehsan , Badawy Haytham , Yousry Yousra

Introduction: In virilized females with Congenital Adrenal Hyperplasia (CAH), the principal aims of surgery are to reduce the size of clitoris, create a vaginal orifice that will allow menstrual flow and intercourse, and to correct the urogenital sinus to prevent incontinence.Surgical techniques evolved with time to make not only "cosmetically accepted" genitalia but also normally functioning. The complications of feminizing geni...

hrp0089p2-p375 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P2 | ESPE2018

Could Basal AMH Replace hCG Stimulation Test in XY Disorder of Sex Development Cases

Elsayed Shaymaa Raafat , Abdo Magdy Omar , Badawy Haytham Elmetwaly , Abbassy Hadeer Aly , Yaseen Duaa Khatter

Background: Traditionally, the standard endocrinological evaluation of 46, XY DSD cases is based upon measurement of testosterone, dihydrotestosterone and androstenedione and their ratios either in mini-puberty or under human chorionic gonadotropin (hCG) stimulation. However, this method is of limited value in reaching definite diagnosis in many cases. More recently, there is a growing appreciation of the value of assessing Sertoli cell function because the most active compart...