hrp0086p2-p707 | Endocrinology and Multisystemic Diseases P2 | ESPE2016

The Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Non-High-Density Lipoprotein Cholesterol Reference Data for Korean Children and Adolescents: Results of the 2007–2013 Korean National Health and Nutrition Examination Surveys (KHANES)

Kang Min Jae , Baek Joon Woo , Oh Yeon Joung , Hwang Il Tae , Yang Seung

Background: Cholesterol levels are variable throughout childhood and adolescence. The attention not only to conventional lipid profiles but also to non-high-density lipoprotein cholesterol (non-HDL-C) and triglyceride to HDL-C ratio (TG/HDL-C ratio) are becoming more apparent in pediatric lipid studies because of their clinical importance.Objective and hypotheses: The aim of the present study was to establish age- and gender-specific reference values for...

hrp0086p1-p727 | Pituitary and Neuroendocrinology P1 | ESPE2016

Changes of Serum AMH and Inhibin B Levels in Girls with Central Precocious Puberty before and During Treatment with GnRH Agonists

Oh Yeon Joung , Baek Joon Woo , Kang Min Jae , Yang Seung , Hwang Il Tae

Background: In girls with central precious puberty (CPP), the hypothalamic-pituitary-gonadal axis is prematurely activated. If the girl is treated with GnRH agonist (GnRH-a), gonadotropins levels become suppressed.Objective and hypotheses: We aimed to evaluate whether serum antimu llerian hormone (AMH) and inhibin B levels are affected in girls with CPP and whether pituitary suppression by GnRH-a affects serum AMH and inhibin B levels.<p class="abste...

hrp0084p3-706 | Diabetes | ESPE2015

Hearing Changes in Children and Adolescents with Type 1 Diabetes Mellitus

Rhie Young-Jun , Baek Joon Woo , Nam Hyo-Kyoung , Lee Kee-Hyoung

Background: There have been reports that patients with diabetes have hearing loss greater than those without. Suggested pathogenesis for diabetes-associated hearing loss has included cochlear microangiopathy, hyperglycaemia of cerebrospinal fluid, auditory neuropathy and diabetic encephalopathy.Objective and hypotheses: This study is aimed to investigate hearing changes in children and adolescents with type 1 diabetes mellitus and to examine if hearing c...

hrp0084p3-1142 | Puberty | ESPE2015

Qualitative Assessment of Precocious Puberty-Related UCC (User Created Contents) on YouTube

Nam Hyo-Kyoung , Bang Soo Min , Baek Joon Woo , Rhie Young-Jun , Lee Kee-Hyoung

Background: Precocious puberty is one of the fastest-growing paediatric diseases in South Korea. As the UCC (User Created Contents) has provided lots of medical information, it becomes an easy and important source of medical information.Objective and hypotheses: This study aimed to investigate and to evaluate the quality and scientific accuracy of precocious puberty-related UCC on Youtube.Method: The key words ‘precocious pube...

hrp0086p2-p659 | Growth P2 | ESPE2016

Influences of GHR-Exon 3 and -202 A/C IGFBP3 Polymorphisms on 1 Year Follow-Up Outcome of Growth Hormone Treatment in Korean Children with Growth Hormone Deficiency

Baek Joon Woo , Oh Yeon Joung , Kang Min Jae , Shim Young Suk , Hwang Il Tae , Yang Seung

Background: The GHR-exon3 and the -202 A/C IGFBP3 polymorphisms have been suggested to affect responses to recombinant human GH (rhGH) therapy in some individuals with short stature. This study aimed to assess the influences of the two polymorphisms on treatment outcomes in patients with GH deficiency (GHD).Method: In 72 (32 girls and 40 boys) children with confirmed diagnosis of GHD, genotyping and serial measurements of auxological and endocrinological...

hrp0086p1-p733 | Pituitary and Neuroendocrinology P1 | ESPE2016

The Influences of Circulating Leptin, Kisspeptin, and Neurokinin B Levels to Precocious Puberty in Obese Girls

Kang Min Jae , Kim Eun Young , Oh Yeon Joung , Baek Joon Woo , Yang Seung , Hwang Il Tae

Background: Leptin has a major role in the metabolic gating of pubertal maturation. Kisspeptin is an essential gatekeeper of puberty. Neurokinin B (NK B) is not widely known in the precocious puberty (PP) but it is coexpressed with kisspeptin in the arcuate nucleus and synchronizes the pulsatile secretion of kisspeptin.Objective and hypotheses: Leptin, kisspeptin, and NK B are influenced by energy balance and metabolic status has a clear impact on the ti...