hrp0089p2-p333 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

Determination of Urinary Metabolic Profiles of Children with Central and Peripheral Precocious Puberty

Balcı Aylin , Recber Tuba , Nemutlu Emirhan , Buluş Derya , Kır Sedef , Gumuşel Belma Kocer , Erkekoğlu Pınar

Puberty is a physical, hormonal and psychosocial transition from childhood to adolescence. Precocious puberty (PP) is the beginning of secondary sexual characteristics before eight years of age in girls. The most common type is known as “central precocious puberty (CPP)”. CPP occurs due to early activation of the hypothalamus-pituitary-gonad (HPG) axis. Although the real trigger for idiopathic CPP is unknown, it has been proposed that it may be caused by the interact...