hrp0086p2-p440 | Gonads & DSD P2 | ESPE2016

An Uncommon Case of Adolescent with POF

Queirolo Sara , Balice Piero

Background: Premature ovarian failure (POF) is uncommon in pediatrics and when occurs during the adolescence is typically iatrogenic or due to chromosomal anomaly. Also many genes have been identified that contribute to the development of POF, and most of these mutations are extremely rare.Objective: We describe a case of 15 years old female presented short stature and secondary amenorrhea, after a normal puberty but without peak height velocity. She was...

hrp0082p3-d2-644 | Adrenals & HP Axis (1) | ESPE2014

Cushings Syndrome without Origin

Queirolo Sara , Balice Piero

Background: Cushings syndrome is a rare entity in children and generally it presents a female to male predominance. The most common cause in childhood is iatrogenic Cushings syndrome related to chronic administration of glucocorticoids or ACTH. Endogenous Cushings syndrome is divided into ACTH dependent (ACTH overproduction due to pituitary adenoma or ectopic production) and in ACTH independent causes (surrenal adenoma, carcinoma, or bilateral hyperplasia).<p class="abstex...

hrp0084p3-1124 | Pituitary | ESPE2015

Sequelae in Giant Prolactinoma in a Teenage Boy

Queirolo Sara , Balice Piero

Background: Macroprolactinomas are rare during childhood. Hypopituitarism is a common feature and recovery of pituitary function was reported following cabergoline therapy.Objective: We present a case of 13 year-old boy with macroprolactinoma who responded to cabergoline therapy with a complete regression of the tumor with a partial empty sella.Results: He complained of a decreased of right vision since 1 year. Evaluation of anteri...