hrp0092p1-130 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019
In vivo and In vitro study of 17β Estradiol Against Amyloid Beta Neurotoxicity in Synaptosomes of Aging Female Rats: A Therapeutic Potential Drug for Parkinson's Disease
Objectives: The aim of the present study was to determine the effects of neuropeptide, neurokinin B (NKB) and amyloid beta fragment Aβ (25-35) on 17β estradiol (E2) treated aging female rat brain of 3 months (young), 12 months (adult) and 24 months (old) age groups.Methods: The aged rats (12 and 24 months old) were given subcutaneous injection of E2 (0.1 µg/g body weight) for 30 days. Synaptosomes we...
ESPE Abstracts
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