ESPE Abstracts

Background: Central precocious puberty (CPP), early fast puberty (EFP) and early puberty (EP) are considered as deviations from normal variability of pubertal tempo. Gonadotropin releasing hormone agonists (GnRHa) have been considered the treatment of choice for CPP for decades, and later for EFP. Several pharmaceutical formulations of GnRHa have been developed, differing in the route and frequency of administration. Treatment was administered mainly by intra-...

Background: A finding of an enlarged clitoris in a female newborn, raises the suspicion of abnormal sexual differentiation and the possibility of female virilization, most commonly due to CAH. This often leads to an extensive medical evaluation which can be painful, expensive, and stressful for the patient and her family. Medical literature does not provide accurate values of a normal clitoris size. According to the few studies available, the current norm rang...