hrp0095p1-266 | Fat, Metabolism and Obesity | ESPE2022
Hinton Elanor
, Elsworth Rebecca
, Bedford Holly
, Hawton Katherine
, Narayan Kruthika
, Naeem Nimra
, Elson Ruth
, Taylor-Miller Tashunka
, Lithander Fiona
, Hamilton-Shield Julian
, Crowne Elizabeth
Background: Craniopharyngioma is a non-malignant, embryological brain tumour in the sellar and parasellar region. Hypothalamic damage is common and accompanied by development of obesity in at least 50% of cases. Mechanisms underlying hypothalamic obesity in craniopharyngioma patients however remain unclear and treatment options are invasive and limited. This feasibility study included a novel application of functional neuroimaging, an established method in obe...