hrp0095p1-379 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

The effect of timing of puberty suppression on breast development in trans girls; a cross-sectional study

Boogers Lidewij , Sardo Infirri Sebastiaan , Bouchareb Asma , de Blok Christel , Liberton Niels , van Trotsenburg Paul , Dreijerink Koen , den Heijer Martin , Wiepjes Chantal , Hannema Sabine

Context: For transgender women undergoing gender-affirming hormone therapy (HT), breast development is an important treatment outcome. Since earlier studies showed small breast volumes in trans women treated with HT, we hypothesized that testosterone exposure during puberty might negatively influence breast development and that early initiation of puberty suppression (PS) might have a positive effect on breast development.Aim:</s...