hrp0097p1-521 | Growth and Syndromes | ESPE2023

A variant of uncertain significance in HMGA2 gene, in a 2-year-old child with Silver Russel syndrome like phenotype - a case report

Bourousis Evangelos , Xatzipsalti Maria , Lazaros Leandros , Nitsos Nikolaos , Stamogiannou Lela

Introduction: Silver-Russell syndrome 5 (SRS5) is characterized by asymmetric intrauterine growth restriction (IUGR), poor postnatal growth, macrocephaly at birth and feeding difficulties. Other possible features include triangular shaped face, prominent forehead, hypertelorism, epicanthus, micrognathia, brachydactyly, clinodactyly of the 5th hand finger, and syndactyly of the 2nd and 3rd toe fingers. Pathogenic variants of the HMGA2 gene, on chromoso...

hrp0095p1-238 | Diabetes and Insulin | ESPE2022

Faster-acting insulin Fiasp vs insulin Novorapid in type 1 diabetes children and adolescents with sensor-augmented pump therapy

Xatzipsalti Maria , Triantafillidou Antigoni , Kourousi Giannoula , Patouni Konstantina , Bourousis Evangelos , Kassari Elisavet , Delis Dimitrios , Vazeou Andriani

Introduction: Rapid-acting insulin analogues have been developed to mimic more closely the physiological action of endogenous insulin. However, they still have a delayed onset of action and a longer duration compares to endogenous insulin. Therefore, newer insulin analogues have been developed with a faster onset and a shorter duration of action.Aim: To evaluate the efficacy of rapid-acting insulin analogues (Novorapid) ...