ESPE Abstracts

Introduction: Pseudohypoaldosteronism (PHA) is a clinical syndrome characterized by multiorgan or isolated renal tubular resistance to the effects of aldosterone, resulting in hyperkalemia, metabolic acidosis, and normal to high serum aldosterone levels. PHA may be primary (hereditary) or secondary (acquired). Primary forms are subclassified into two: PHA type 1 (salt-wasting) and PHA type 2 (salt-retaining). Secondary forms are typically associated with sever...

Type 1 diabetes (T1D) is considered as the most common autoimmune chronic metabolic disease in childhood with constantly rising incidence in last decades. Many studies have confirmed the role of natural killer cells (NK) in the autoimmune destruction of the pancreatic beta cells The aim of the study was to evaluate the serum levels of NK cells in Bulgarian children with T1D from Pleven region and to assess their correlation with the metabolic control and diabetes duration<...