hrp0098p1-263 | Growth and Syndromes 4 | ESPE2024

Reduced final height in boys after allogeneic hematopoietic stem cell transplantation (HSCT) for childhood cancer: does pubertal growth spurt matters?

Ferrari Vittorio , Cantarelli Erika , Leardini Davide , Brandi Alessia , Ortolano Rita , Baronio Federico

Introduction: Growth failure is a side effect of HSCT in children. This study aims to evaluate the growth trajectory in a series of boys who underwent allogeneic HSCT for childhood cancer in pre-puberty and reached final height (FH).Methods: We evaluated auxological parameters, mid-parental target height (TH), serum testosterone, and insulin-like growth factor 1 (IGF-1 SDS) levels of 19 boys who underwent allogeneic HSCT...