ESPE Abstracts

Background: Acute lymphoblastic leukemia (ALL) is the most common paediatric cancer. Skeletal morbidity has been recognized as a complication of ALL and its treatment, occurring at diagnosis, during chemotherapy and/or years later.Aim: To describe the adversely effect on bone health, in terms of vertebral fractures (VF) and bone mineral density (BMD), in the follow-up of children with ALL.Design, patients and methods: Descriptive a...

Due to the increase in prevalence of childhood obesity, more obese children are referred to the endocrinologist for the hypothalamus-hypophysis-adrenal axis assessment. The circadian rhythm (CR) of cortisol in saliva (SAF) may constitute a non-invasive, first line test to exclude hypercortisolism on obese children.Aim: To evaluate possible disturbances of CR of SAF in obese children with clinical signs of hypercortisolism.<p class="a...

Introduction: Haematological malignancies represent the most frequent cancer in children. While there is an extensive literature on testicular function in adult survivors of childhood cancer, focused on sperm and androgen production, scarce information exists on the immediate impact in prepubertal boys.Aim: To characterise testicular function, focused on Sertoli cell biomarkers, from diagnosis up to 3 years after the end...