hrp0098p2-147 | GH and IGFs | ESPE2024

Is somatotropin therapy lowering the risk of SARS-CoV-2 infection in children with growth hormone deficiency and idiopathic short stature?

Bril Gherta , Bril Paroz Roberta

COVID-19 is a worldwide pandemic caused by SARS-CoV-2, to which adults are usually more susceptible than children. Growth hormone (GH) levels differ between children and adults and decrease with age. There is bidirectional crosstalk between the GH/insulin-like growth factor-1 (IGF-1) pathway and the immune system that plays a significant role in SARS-CoV-2 infection. We evaluated the association between somatotropin treatment (GH replacement therapy) and the risk for SARS-CoV-...