hrp0095p2-139 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

A stormy neonatal course

Brown Katie , Kaninde Abhidhamma , Law James , Nadar Ruchi , Saraff Vrinda , Mohamed Zainaba

Introduction: Neonatal thyrotoxicosis (NT) is rare but potentially life-threatening condition with high mortality risk due to cardiac failure(12-20%). Affected neonates are born to mothers with underlying thyroid pathology. Estimated prevalence of trans-placental transfer of thyroid antibodies occurs 1 in every 70 pregnancies with Graves’ disease. Symptoms in the neonate usually manifest by 10 days of life but this can be as late as day 45. We discuss tw...