hrp0084p2-406 | GH & IGF | ESPE2015
van der Steen M
, Lem A J
, van der Kaay D C M
, Waarde W M Bakker-van
, van der Hulst F J P C M
, Neijens F S
, Noordam C
, Odink R J
, Oostdijk W
, Schroor E J
, Sulkers E J
, Westerlaken C
, Hokken-Koelega A C S
Background: Previously we showed that pubertal children born small for gestational age (SGA) with a poor adult height (AH) expectation can benefit from treatment with GH 1 mg/m2 per day (~0.033 mg/kg per day) in combination with 2 years of GnRH analogue (GnRHa) and even more so with a double GH dose. GnRHa treatment is thought to have negative effects on body composition and blood pressure. Long-term effects and GH-dose effects on metabolic health in children treate...