hrp0098rfc9.4 | Sex Endocrinology and Gonads | ESPE2024

Testicular function in prepubertal boys with haematological malignancies during and post chemotherapy: a prospective, longitudinal study

C. Lopez Dacal Jimena , Prada Silvina , Brenzoni Luciana , Arozarena María , Gabriela Ropelato María , Gabriela Ballerini María , Eugenia Rodriguez María , Soria Marcela , Ferraro Cristina , Bedecarrás Patricia , Drelichman Guillermo , Aversa Luis , Bergadá Ignacio , A. Rey Rodolfo , P. Grinspon Romina

Introduction: Haematological malignancies represent the most frequent cancer in children. While there is an extensive literature on testicular function in adult survivors of childhood cancer, focused on sperm and androgen production, scarce information exists on the immediate impact in prepubertal boys.Aim: To characterise testicular function, focused on Sertoli cell biomarkers, from diagnosis up to 3 years after the end...