hrp0095p1-116 | Growth and Syndromes | ESPE2022

Clinical and biochemical parameters of puberty onset in children with Silver Russell syndrome and children born small for gestational age

Patti Giuseppa , Malerba Federica , Scaglione Marco , Schiavone Maurizio , Grazia Calevo Maria , Varotto Carolina , Casalini Emilio , Fava Daniela , Allegri Anna , Napoli Flavia , Di Iorgi Natascia , Maghnie Mohamad

Silver-Russell syndrome (SRS) is a rare heterogeneous syndrome associated with severe prenatal and postnatal growth retardation.Context: There is little information on puberty onset and bone age trend in children with SRS.Study Design and partecipants: Retrospective observational study, including patients with a confirmed diagnosis of SRS divided in 2 molecular groups [ 11p15 loss of methylation, (...

hrp0098p1-286 | Thyroid 3 | ESPE2024

Has COVID-19 Changed Pediatric Graves' Disease? A Study Investigating Post-Pandemic Trends

Alessandro Naim , Silvia Merlo , Zonca Viviana , Naim Sara , Calevo Mariagrazia , Varotto Carolina , Casalini Emilio , Fava Daniela , Elsa Maria Allegri Anna , Angelelli Alessia , Napoli Flavia , Tedesco Caterina , Di Iorgi Natascia , Gastaldi Roberto , Maghnie Mohamad

Introduction: Graves'disease (GD) is the most common cause of hyperthyroidism in pediatric populations. Recent observations at our tertiary center suggest a potential increase in pediatric GD cases following the COVID-19 pandemic. This single-center study aims to investigate the potential increase in GD cases and explore any significant differences in clinical presentation and outcomes before and after the onset of COVID-19 pandemic.<p class="abstext"...