hrp0098rfc3.1 | Pituitary, Neuroendocrinology and Puberty 1 | ESPE2024

DNA Methylation profiles in girls with anorexia nervosa and amenorrhea: a pilot study

Palumbo Stefania , Palumbo Domenico , Giurato Giorgio , Cirillo Grazia , Aiello Francesca , Miraglia del Giudice Emanuele , Carotenuto Marco , Salerno Filomena , Grandone Anna

Background: In the published literature, eating disorders appear as a cause of pubertal delay/arrest in young girls. Furthermore, several studies associate anorexia nervosa (AN) with epigenetic changes that may heighten the risk of the disorder and lead to clinical signs as functional hypothalamic amenorrhea. In the present study we investigated whether AN correlates with a distinct DNA methylation profile compared to normal-eating pubertal girls.<p class=...