ESPE Abstracts

Introduction: Congenital adrenal hyperplasia (CAH) is a family of autosomal recessive disorders caused by an inherited defect in cortisol biosynthesis, 90-99% of CAH cases occur due to 21-hydroxylase deficiency, while 11β-hydroxylase deficiency (11βOHD) accounts for only 0.2-8% of cases. In this study, we report a case of congenital adrenal hyperplasia due to 11βOHD in a two-year-old boy who presented with pseudo precocious puberty and tall stat...

Introduction: The glycated hemoglobin (HbA1c) corresponds to the fraction of Hb exposed to non-enzymatic glycation of the N-terminal part of the beta chain of Hb A, in case of elevation of blood sugar. Any change in erythropoiesis and/or lifetime of red blood cells will affect the reliability of HbA1c levels.Case presentation: 12-year-old girl followed for growth homone deficiency, under growth hormone, in whom the annua...

Background: Growth hormone deficiency (GHD) in children is a rare condition. It may be idiopathic or may develop as a consequence of congenital or acquired organic pathology of the hypothalamic-pituitary axis. GHD can be partial or part of a combined pituitary deficiency. Brain magnetic resonance imaging (MRI) is very useful in establishing the etiology of GHD and predicting its severity.Study aims: To investigate the re...

Introduction: Several predictive factors of response to rGH have already been described in the literature such as age and height at the beginning of treatment, rGH dose and parental height status. However, few data exist on the predictive value of pre-therapeutic data on the response to rGH.The main objective of the study: is to identify predictive factors of the rGH response in children with GHD, with a particular inter...