hrp0098p3-57 | Diabetes and Insulin | ESPE2024

Management of a clinical case of type 1 diabetes in the pre-asymptomatic stage

Arvanitaki Theodosia , Karabouta Zacharoula , Benioudakis Emmanouil , Chinou Panagiota

Introduction: Disease-modifying agents, such as anti-CD3 monoclonal antibodies, have shown promising outcomes in improving the management of Type 1 Diabetes (T1D). Immunotherapy with teplizumab has delayed the onset of T1D for three years. It is been administered intravenously for 14 days in children and young people (CYP) aged > eight years already in stage 2 (multiple islet autoantibodies, abnormal glucose tolerance, usually pre-symptomatic). This treatme...