hrp0084p3-820 | Endocrine Oncology | ESPE2015

AIP Polymorphism in Familiar Isolated Pituitary Adenomas: Case Report

Viale Maria Lorena , Hernandez Claudia L , Rampi Maria Gabriela , Serra Maria Pia , Figueroa Veronica , Day Patricia Fainstein , Brunetto Oscar H

Background: Familiar isolated pituitary adenomas (FIPA) encompasses the familiar occurrence of isolated pituitary adenomas outside the setting of syndromic conditions such as MEN1 and Carney’s complex, and comprise about 2–3% of pituitary adenomas. About 20% of FIPA have mutations in the aryl hydrocarbon receptor interacting protein gene (AIP), usually associated with a worse outcome.Objective and hypotheses: Evaluate the presence of AIP gene m...