hrp0082fc3.6 | Diabetes | ESPE2014

Alpha-Lipoic Acid and Anti-Oxidant Diet Helps to Improve Endothelial Dysfunction in Children and Adolescents with Type 1 Diabetes

Scaramuzza Andrea , Ungheri Saverio , Redaelli Francesca , Bosetti Alessandra , Giani Elisa , Ferrari Matteo , Comaschi Valentina , Giudici Valentina , Zuccotti Gian Vincenzo

Background: Endothelial dysfunction is a macrovascular complication of type 1 diabetes. Children and adolescents with type 1 diabetes may suffer of endothelial dysfunction, irrespective of chronological age and disease duration.Objective and hypotheses: After evaluating the prevalence of early endothelial dysfunction, as measured by mean of reactive hyperaemia in adolescents with type 1 diabetes, at baseline and after 1-year follow-up, we started a 6-mon...