hrp0098p2-15 | Adrenals and HPA Axis | ESPE2024

Premature Adrenarche, Body Composition and Metabolic Dysfunction – Characterisation of a Pilot Cohort

Ben Said Wogud , Cooper Lucy , Campbell-Hamilton Eloise , Parry Emma , Krone Ruth , Thangaratinam Shakila , Crabtree Nicola , Arlt Wiebke , Idkowiak Jan

Introduction: Early-onset androgen excess commonly presents in pre-pubertal girls as premature adrenarche (PA). Girls with PA have clinical signs of androgen excess, such as pubic/axillary hair, body odour, greasy hair, and moderately elevated adrenal androgens before their 8th birthday. There is conflicting evidence if girls with PA are at higher risk to have or develop metabolic dysfunction, or progress to developing Polycystic Ovary Syndrome (PCO...