hrp0098p3-189 | Multisystem Endocrine Disorders | ESPE2024

Endocrinological sequelae of protein-losing enteropathy in an italian child

Cavarzere Paolo , Mancioppi Valentina , Battiston Riccardo , Lupieri Valentina , Cristofaletti Alessandra , Morandi Anita , Maffeis Claudio

Background: Protein-losing enteropathy (PLE) is a complex life-threatening complication that occurs in 5-15% of patients who undergo Fontan procedure to palliate a functional or anatomic single ventricle. Patients with PLE suffer from enteric protein loss, hypoproteinemia, hypoalbuminemia and electrolyte alterations. Enteral budesonide is widely recognized as the corticosteroid of choice to treat gut inflammation underlying PLE for its strong local anti-inflam...