hrp0089fc1.4 | Adrenals & HPA Axis | ESPE2018
, Marinakis Nikos
, Nicolaides Nicolas C.
, Crousos George
, Charmandari Evangelia
Introduction: Primary Generalized Glucocorticoid Resistance or Chrousos syndrome (CS) is a rare sporadic or familial disorder characterized by generalized, partial tissue insensitivity to glucocorticoids. Mutations of the NR3C1 gene, which encodes the human glucocorticoid receptor, have been identified in many but not all patients with CS.Objective: To identify novel genes related to CS in patients without NR3C1 gene mutations.<p cl...