hrp0092p2-175 | Growth and Syndromes (to include Turner Syndrome) | ESPE2019

The Impact of Growth Hormone Treatment in Patients with Noonan Syndrome and Growth Hormone Deficiency

Sang Lee Hae , Bae Sohn Young , Dae Kum Chang , Sub Lim Jung , Soon Hwang Jin

Purpose: Noonan syndrome (NS) is a genetic disorder characterized by specific features including short stature, cardiac defect, and distinctive facial dysmorphism. Human growth hormone (GH) has been used to improve growth in children with NS but there is little information how GH treatment affects height. The aim of this study is to investigate efficacy of GH treatment in Korean children with NS compared to sex and age-matched patients with growth hormone defi...