hrp0089fc4.6 | GH & IGFs | ESPE2018
Rasmussen Michael Hojby
, Damholt Birgitte Bentz
, Helleberg Hans
, Bjelke Mads
, Suresh Swapna
, Juul Rasmus Vestergaard
, Hollensen Christian
Background: Somapacitan is a reversible albumin-binding growth hormone (GH) derivative in clinical development for once-weekly administration in patients with GH deficiency (GHD). Clinical data in healthy subjects, and adults and children with GHD showed that once-weekly somapacitan injections were well tolerated with no clinically significant safety or local tolerability issues. A sustained dose-dependent IGF-I response supports a once-weekly treatment regimen.<p class="a...