hrp0086fc12.1 | Neuroendocrinology | ESPE2016
, Harbulot Carole
, Csaba Zsolt
, Jacquier Sandrine
, de Roux Nicolas
Background: Acquisition and maintenance of fertility in mammals rely on the function of Gonadotropin Releasing Hormone (GnRH) neurons. During the juvenile period, GnRH neurons undergo morphological maturation, which involves changes in synaptic inputs and neuropeptide activation from afferent neurons. The functional importance of this maturation could be a pre-requisite for puberty onset. However, the mechanisms behind these dynamic changes have yet to be identified.<p cla...