ESPE Abstracts

Background: Several criteria for growth response to growth hormone (GH) therapy have been developed. These include height velocity (HV), height standard deviation score (HSDS), ΔHV, and ΔHSDS. Other parameters considered as predictors of growth response include age at start, weight SDS, GH dose, and target height SDS. Among these, the two most important parameters to predict future height before treatment start are HSDS and age.<p class="abstex...

Introduction: Children with Prader-Willi syndrome present with short stature and obesity. However, very little is known about the role of this imprinted control region in the general population. This study aims to analyze the methylation status of the PWS imprinting control region (ICR) in placenta and its association with postnatal growth and obesity parameters in healthy children.Methodology: The methylation percentages of the PWS-ICR ...