ESPE Abstracts

Thalassemia is a common genetic blood disease that is characterized by a decrease or absence of normal globin chain synthesis. This results in an imbalance of alpha and beta globin chain synthesis, leading to ineffective erythropoiesis and hemolysis, which causes anemia. The severe form of thalassemia is called thalassemia major and is usually associated with lifelong transfusion-dependent anemia. The incidence rate of thalassemia is higher in the Middle East, and it is a majo...