hrp0098s12.1 | The impact of gonadotrophin dysregulation on neurocognition | ESPE2024

The Role of MiniPuberty in Non-Reproductive Outcomes

Chachlaki Konstantina , Messina Andrea , Delli Virginia , Dehame Julien , Leysen Valerie , Storme Laurent , Carleton Alan , Santoni Federico , Pitteloud Nelly , Prevot Vincent

Minipuberty, a transient activation of the hypothalamic-pituitary-gonadal (HPG) axis during early infancy, plays a critical role beyond reproductive development. Recent evidence suggests that minipuberty, in addition to facilitating the process by which the capacity for sexual reproduction is achieved and maintained, may also influence neurodevelopmental programming and the maintenance of sensory (e.g., olfaction and hearing) and cognitive performance throughout life. During m...