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hrp0089p3-p172 | Fetal, Neonatal Endocrinology and Metabolism P3 | ESPE2018

Forty patients with persistent, non-focal congenital hyperinsulinism: Urgent need for new treatment modalities

Rasmussen Amalie Greve , Melikian Maria , Globa Evgenia , Detlefsen Sonke , Rasmussen Lars , Petersen Henrik , Brusgaard Klaus , Rasmussen Annett Helleskov , Christesen Henrik

Background: Congenital hyperinsulinism (CHI) is a rare, heterogeneous disease with a focal, diffuse, or atypical histological form and a high risk of cerebral injury due to severe hypoglycemia.Methods: We retrospectively evaluated the treatment and outcome of a cohort of patients with non-focal, persistent CHI admitted to the International Hyperinsulinism Center, Denmark from January 2000 to May 2017. Data were extracted from hospital files.<p class=...

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hrp0097rfc10.5 | Fetal, neonatal endocrinology and metabolism (to include hypoglycaemia) & Multisystem endocrine disorders | ESPE2023

Insulinoma in childhood: A multicenter retrospective study of 28 patients

Melikyan Maria , Gubaeva Diliara , Shadrina Anna , Bolmasova Anna , Kareva Maria , Tiulpakov Anatoly , Gurevich Larisa , Efremenkov Artem , Averyanova Julia , Andersen Kirstine , Brusgaard Klaus , Detlefsen Sonke , Christesen Henrik

Background: Insulinomas are very rare in childhood with sparse knowledge on the clinical aspects and the presence of Multiple Endocrine Neoplasia type 1 (MEN1).Methods: We conducted a multicentre retrospective review of patients diagnosed with insulinoma between 1995-2021. Clinical, biochemical, genetic, imaging and histological data were collected. In addition, follow-up and family data were obtained.<p class="abste...

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ESPE Abstracts

Forty patients with persistent, non-focal congenital hyperinsulinism: Urgent need for new treatment modalities

Insulinoma in childhood: A multicenter retrospective study of 28 patients

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