hrp0095p1-239 | Diabetes and Insulin | ESPE2022

Why understanding hemoglobin glycated measurement can be important: Santa Juana hemoglobin variant and falsely elevated HbA1c

Lorand Juan , Boutsen Laure , Gueulette Emmanuelle , Maisin Diane , Closset Mélanie , Mouraux Thierry , Beckers Dominique

Diabetes mellitus is a chronic disease. The risk of microvascular complications is correlated with hemoglobin A1c (HbA1c) level [1] Educating the diabetic patient to keep an HbA1c below 7% reduce the risk of long-term complications. We report the case of a 15 years old teenager, with chronical headache, referred for diabetes mellitus with a fasting glycemia of 83 mg/dl (normal < 100) and an HbA1C of 8.3% using an Ion-exchange High Performance Liquid Chromatography (HPLC, Ad...