hrp0098fc12.2 | Thyroid | ESPE2024

Molecular Characterization of Childhood Thyroid Nodules and Thyroid Cancer with DNA/RNA Next Generation Sequencing and Investigation of Phenotype-Genotype Correlation

Aycan Zehra , Kızılcan Çetin Sirmen , Karadağ Kıvrak Hale , Ceyhan Koray , Şıklar Zeynep , Berberoğlu Merih , Özsu Elif , Suat Fitöz Ömer , Dizbay Sak Serpil

Background: Our study aimed to determine the molecular characterization of thyroid nodules and cancer in childhood and investigate the genotype-phenotype relationship.Methods: The pre-postoperative clinical follow-up features and genetic characteristics of 62 patients were evaluated. Next-generation sequencing (NGS) was used to investigate common variants in thyroid lesions with sufficient tissue in the pathology archive...