hrp0086rfc5.4 | Management of Disorders of Insulin Secretion | ESPE2016
Busiah Kanetee
, Baz Baz
, Lebourgeois Fleur
, Djoudi Malek Ait
, Bachere Nadege
, Bourron Olivier
, Ythier Hubert
, Pouvreau Nathalie
, Bellanne-Chantelot Christine
, Vialettes Bernard
, Gourdy Pierre
, Hartemann Agnes
, Robert Jean-Jacques
, Cave Helene
, Polak Michel
, Gautier Jean-Francois
Background: “Transient” Neonatal Diabetes Mellitus (TNDM) is a rare genetic beta cells dysfunction leading to hyperglycaemia that resolves in early childhood. About 80% of patients relapse during adolescence or adulthood. Glucose homeostasis had not been investigated in adulthood.Objective and hypotheses: To investigate insulin secretion and insulin sensitivity in adults affected with TNDM or in their 1st degree mutated relatives.</p...