hrp0098p2-216 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

The comparison of the timing of menarche in girls with central precocious puberty following the discontinuation of monthly and 3-monthly Leuprolide acetate.

Nakaviroj Ekkachai , Thaneetrakool Thanaporn , Srilanchakon Khomsak

Introduction: Central precocious puberty (CPP) is typically treated with gonadotropin-releasing hormone (GnRH) agonists. Although there are numerous GnRH agonist variants available, there is limited research comparing the timing of menarche in girls treated with monthly (3.75 mg) versus 3-monthly (11.25 mg) Leuprolide acetate. The objective of this study was to evaluate the timing of menarche after the administration of monthly and 3-monthly Leuprolide acetate...