hrp0092p3-140 | GH and IGFs | ESPE2019

Assessment of Body Composition of Children with Short Stature on Growth Hormone Therapy and its Relation to Serum IGF-1

El-Hawary Amany , osman Engy , El-Eshmawi Ahmed

Background: Isolated Growth Hormone Deficiency (IGHD) is a common endocrinal cause of pediatric short stature. Growth hormone produces most of its actions via insulin growth factor 1 (IGF-1) which affected in IGHD. GH can affect body composition via its action on body metabolism.Objectives: This study aimed to prospectively assess body composition among IGHD group starting GH replacement and after six month of therapy ve...

hrp0084p3-1157 | Puberty | ESPE2015

Assessment of Endocrine Function in Egyptian Adolescent B-Thalassemia Major Patients

Dayem Soha Abd El , Kader Mona Abd El

Objective: To evaluate the endocrine function among Egyptian adolescent thalassemic patients.Patients and methods: 54 patients and 28 age-matched normal controls was included. Anthropometric measurements, clinical pubertal assessment were done for all patients. Oral glucose tolerance test (OGTT) was done to all patients and controls with measuring serum insulin level at 0.120 minutes. Insulin sensitivity and release index were calculated. 32 patients had...

hrp0092p2-17 | Adrenals and HPA Axis | ESPE2019

Duodenal Web Presenting as Pseuhypoaldosteronism in Infancy

El Bejjani Mireille , Thalange Nandu

Case Report: A 5-month-old girl born to first-cousin parents was referred to endocrinology for evaluation following two hospitalizations for vomiting and dehydration with severe hyponatremia and hyperkalemia. She had a history of recurrent emesis and poor weight gain, with a reportedly normal abdominal and renal ultrasound.Initial evaluation showed hyponatremia with elevated renin 170 ng/ml/hr (normal 2-37 ng/ml/hr) and aldosterone 275 n...

hrp0084p2-253 | Diabetes | ESPE2015

Value of the Intrarenal Arterial Resistivity Indices and Different Renal Biomarkers for Early Identification of Diabetic Nephropathy in Type 1 Diabetic Patients

Battah Ahmed , Dayem Soha Abd El , Bohy Abo El Magd El , Shohaby Amal El , Allah Nagwa Abd

Objective: To compare resistivity index (RI) in type 1 diabetic patients and normal controls, secondly to evaluate whether high RI is associated with different biomarkers of diabetic nephropathy (DN) as early detection of DN offers the best chance of delaying or possibly preventing progression to end-stage renal disease.Patients and methods: The study included 62 type 1 diabetic patients and 30 healthy volunteer of the same age and sex. Blood sample was ...

hrp0095p2-143 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

All Roads Don’t Lead to Rome After All!!

Diab Dina , El Sayed Shaymaa

Abstract: Hypoglycemia is a frequent and one of the major metabolic emergencies in any age, causing a significant dilemma to reach the correct diagnosis and perform the appropriate management. it Has potentially devastating consequences on brain development and cognitive functions. It Is a heterogeneous disorder with many different possible etiologies, including hyper-insulinism, glycogen storage diseases, fatty acid oxidation defects, hormonal deficiencies (g...

hrp0092p3-77 | Diabetes and Insulin | ESPE2019

Factors Affecting the Preservation of C-Peptide Secretion in Egyptian Children with Type 1 Diabetes

El-hawary Amany , Aboelenin Hadil , El-Helaly Rania , El-Gwad Ahmed Abd

Background: type I diabetes is associated with progressive destruction of pancreatic β-cells with gradual decline of insulin secretion. C-peptide is considered the best indicator of endogenous insulin secretion in patients with diabetes.Aim of the Work: evaluate the effect of different variables associated with preserved pancreatic beta cell function at one year after diagnosis of children with type I DM.<p c...

hrp0084p3-720 | Diabetes | ESPE2015

Cardiovascular Autonomic Neuropathy and Early Atherosclerosis in Adolescent Type 1 Diabetic Patient

Battah Ahmed , Dayem Soha Abd El , Bohy Abo El Magd El , Allah Nagwa Abd

Objective: To evaluate cardiovascular autonomic neuropathy (CAN) in type 1 Diabetics and to detect its relation to coronary artery calcification.Patients and methods: It is a cross sectional study included 62 diabetics and 30 controls. Clinical, laboratory assessment and 24 h holter were done for all patients and controls and coronary artery calcium (CAC) scoring by multisclice CT was done for all patients only. t-test, Mann–Whitney U-test ...

hrp0084p3-724 | Diabetes | ESPE2015

Study of Adiponectin Level in Diabetic Adolescent Girls in Relation to Glycaemic Control and Complication of Diabetes

Dayem Soha Abd El , Nazif Hayam K , Kader Mona Abd El , El-Tawil Maha , Battah Ahmed

Objective: To determine the influence of adolescent girls with type 1 DM on circulating levels of adiponectin and to study the relation between adiponectin level with glycemic control and complication of diabetes.Patients and methods: The study included 40 female adolescent type 1 diabetic patients and 40 healthy volunteer of the same age and sex. Blood sample was taken for assessment of glycosylated haemoglobin, lipid profile and adiponectine. Urine sam...

hrp0095p2-27 | Adrenals and HPA Axis | ESPE2022

It is Not Always A Piece of Cake!!

Diab Dina , Sayed Shaymaa El , Marzouq Iman , El Neely Dalia , Alaa Thabet Dalia , Awaa Ahmed El

Introduction: Congenital lipoid adrenal hyperplasia (lipoid CAH), is a rare subtypes of adrenal hyperplasia yet the most fatal form, which seriously disrupts adrenal and gonadal steroidogenesis by a defect in the conversion of cholesterol to pregnenolone. Affected patients show salt loss from impaired mineralocorticoid and glucocorticoid synthesis. The defect in lipoid CAH is mainly in the steroidogenic acute regulatory protein (StAR), which promotes entry of ...