ESPE Abstracts

Objective and hypotheses: To study the lipid metabolism in children with diabetes type 1.Method: It was included 44 children (33 girls), the average age – 10.2±3.3 years. Patients were divided: group 1 (less than 5 years) – 23 children (17 girls), mean age 9.8±3.6, the average length of diabetes 2.08±1.5 years. The second (over 5 years) – 21 children (16 girls), mean age of 11.6±2.4, the average length – 7.5±1...

Background and aims: To study the prevalence of metabolic syndrome and its components (impaired fasting and after overload glucose, type 2 diabetes mellitus, low cholesterol HDL, and high triglycerides) in children with obesity.Methods: This research includes 550 (65.8% boys) children, recruited from Pediatric Endocrinology Department, with abdominal obesity. We measured BMI, waist circumference, blood pressure with standard instrumentation and glucose (...

Objective: The aim of this study were to investigate the level of inhibin B and its relationship with testosterone, anti-Müllerian factor, basal, and GnRH-stimulated gonadotropin hormones (LH and FSH) concentration in boys with constitutional delay of puberty.Material and methods: In the study were included 15 boys (mean age 14.5±1.6 years) in Tanner stages 1–2. The investigation consists of genital examination with prader orchidometer, de...

Background: Disorders of sex development, especially with Y chromosome material, are the main factor of an increased risk of gonadal tumour. The main idea of this study was to investigate the prevalence of gonad tumours in patients with 46,XY gonadal dysgenesis.Methods: This study included 9 patients with 46,XY gonadal dysgenesis: seven patients with partial and two with total gonadal dysgenesis. Among nine patients there were two patients with Frasier s...

Objective: to evaluate clinical and laboratory characteristics of various types of gonadal dysgenesis in girls with hypergonadotropic hypogonadism.Methods: 17 girls with hypergonadotropic hypogonadism (13.9±3.72) were examined. Inclusion criteria: characteristics of delayed puberty, no disorders of sex development, presence of müllerian duct derivatives, high levels of gonadotrophins. Tanner stage, antropometri...

Objective: To study clinical and laboratory characteristics of patients with disorders of sex development (DSD) 45,X/46,XY and 46,XY, partial gonadal dysgenesis.Subjects and Methods: It was included 27 patients with disorders of gonadal dysgenesis at birth to 9 years, which were divided into groups based on cytogenetic survey – DSD 46,XY, partial gonadal dysgenesis (n=10) and DSD 45,X/46,XY (n&...

Objectives: To study predictors of target levels of glycosylated hemoglobin (HbA1c) in children with diabetes mellitus type 1 (DM1), receiving pump insulin treatment.Materials and Methods: 64 children (27 girls, 46 adolescents) with diabetes mellitus type 1 (mean age 12.8±3.5 years, disease duration 4.46±3.1 years, daily insulin dose 0.82±0.24 units) receiving pump insulin treatment for 2.46±1.43 years were studied. The res...

Topic: Compliance for monitoring of glycemic control in children with type 1 diabetes.Background and Aims: To estimate attachment of children with type 1 diabetes to self-control of blood glucose with help of automatically data processing system of glycemic control.Method: We have checked 54 patients with first type diabetes at the age 14±3, 4 years old (32 males, 22 females), divided into two age groups: from 0 to 14, and 15-...

Objective: To examine the clinical and hormonal predictors of start pubertal in boys with constitutional delay of puberty (CDP).Materials and methods: The study included 42 boys with CDP (Tanner1, max LH>10 IU/l of GnRH stimulation test). At the first visit in 14.5±0.7 years we evaluated anthropometric indicators, bone age, testicular volume and hormonal status (TSH, freeT4, prolactin, IGF-1, insulin, DHEAS, cortisol, LH, FSH, estradiol, testost...

Objective and hypotheses: To evaluate endocrine risk factors of testicular cancer of children with testicular microlithiasis.Method: Under research were 74 patients with testicular microlithiasis (average 11.41±4.02). Heredity, case history, endocrine diseases, anthropometric indicators, ultrasound of the scrotum were evaluated.Results: At 20 of 74 (27%) children microlithiasis was combined with strong risk factors of testicle...