hrp0097ha1 | An integrated roadmap of human fetal adrenal gland development | ESPE2023
del Valle Ignacio
, Young Matthew
, Kildisiute Gerda
, Ogunbiyi Olumide
, Buonocore Federica
, Simcock Ian
, Khabirova Eleonora
, Crespo Berta
, Moreno Nadjeda
, Brooks Tony
, Niola Paola
, Swarbrick Katherine
, Suntharalingham Jenifer
, McGlacken-Byrne Sinead
, Arthurs Owen
, Behjati Sam
, Achermann John
Introduction: The human adrenal gland originates from the adrenogonadal primordium at around 4 weeks post conception (wpc) and undergoes marked developmental changes throughout the first half of pregnancy. Several key aspects of adrenal maturation are well-established, such as the formation of a large inner fetal zone (FZ) and synthesis of dehydroepiandrosterone, but many other processes contributing to adrenal gland development and function in humans are stil...