hrp0098p1-227 | Diabetes and Insulin 4 | ESPE2024

Higher levels of c-peptide at the onset of Type 1 Diabetes are correlated with better glycemic control after 2 years from the diagnosis in a cohort of pediatric patients.

Marigliano Marco , Piona Claudia , Mancioppi Valentina , Morotti Elisa , Fornari Elena , Olivieri Francesca , Morandi Anita , Maffeis Claudio

Background and Objective: Diabetic ketoacidosis (DKA) is an acute endocrinological emergency in childhood. It occurs in 20-40% of cases at the onset of Type 1 Diabetes (T1D). DKA is classified as mild, moderate, and severe based on the clinical picture and blood pH levels. This study aims to evaluate the relationship between the characteristics of T1D onset (DKA level, pH, c-peptide) and the glycometabolic control 2, 5, and 10 years after the diagnosis.<p ...

hrp0098p1-228 | Diabetes and Insulin 4 | ESPE2024

The use of pumps with Automated Insulin Delivery (HCL/AHCL) improves the Sleep Quality of Children and Adolescents with Type 1 Diabetes and of their parents/caregivers.

Marigliano Marco , Piona Claudia , Mancioppi Valentina , Morotti Elisa , Fornari Elena , Olivieri Francesca , Morandi Anita , Maffeis Claudio

Background and Objective: Type 1 Diabetes (T1D) is one of the most frequent endocrine-metabolic diseases in children and youth. Several studies assessed Sleep Quality (SQ) in Children with Diabetes (CwD), yielding conflicting results. This study aims to test the hypothesis that the use of glucose sensors and insulin pumps in T1D is associated with better QOL and SQ in a group of CwD and their parents/caregiversSubjects and Method...

hrp0098rfc1.6 | Diabetes and Insulin | ESPE2024

Metabolic dysfunction-associated steatotic liver disease and its association with glycemic control metrics in children and adolescents with type 1 diabetes: an exploratory study

Maffeis Claudio , Piona Claudia , Morandi Anita , Marigliano Marco , Morotti Elisa , Mancioppi Valentina , Zusi Chiara , Emiliani Federica , Mantovani Alessandro , Colecchia Antonio , Targher Giovanni

Context: Metabolic dysfunction-associated fatty liver disease (MASLD) is the most common chronic liver disease. Recent data showed that MASLD is a common condition also in adults with type 1 diabetes (T1D) and it is independently associated with an increased risk of diabetic complications.Aims: To examine the prevalence of MASLD and its association with glycemic control metrics in children and adolescents with T1D.<p...