ESPE Abstracts

Background: Non Hodgkin lymphoma (NHL) is the fourth most common malignancy in childhood. Chemotherapy constitutes the first line treatment and may cause several endocrine side effects (growth retardation, hypergonadotrophic hypogonadism, bone mass loss and rarely secondary malignancy). In total of 1–2% of children may harbour thyroid nodules. The most common risk factors are: irradiation, female sex, iodine deficiency, puberty and past medical history of thyroid disease....

Background: Autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED), is a rare inherited disease of childhood, caused by the mutation of the AIRE gene on chromosome 21. It is characterized by three main diseases: chronic mucocutaneous candidiasis (CMC), chronic hypoparathyroidism (HP), and Addison’s disease (AD), and can be associated with other autoimmune diseases and/or manifestations of ectodermal dystrophy.Case...

Background: Pseudohypoparathyroidism (PHP) is a rare group of disorders characterised by end-organ resistance to parathyroid hormone (PTH), and possibly TSH, with or without features of Albright’s hereditary osteodystrophy.Case presentation: A 14-year-old boy presented with fatigue and spontaneous carpal spasms in association with a febrile viral infection. Past medical history was significant for an episode of asymptomatic hypocalcemia treated with...