hrp0095p1-186 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Inflammation and polycystic ovary syndrome (PCOS). Utilising proteomic analysis to unravel the link between inflammatory proteins and PCOS in adolescents

Gunn Harriet , Oberg Emma , Hällqvist Jenny , Lindén Hirschberg Angelica , Steinbeck Katharine , Mills Kevin

Background and Methods: PCOS is common in adolescents and imparts a significant health and economic burden. Yet, our understanding of its complex pathogenesis is lacking. Proteomic analyses would be a valuable tool to deepen our knowledge of the biological pathways which underpin PCOS, and to identify novel biomarkers to diagnose and monitor this common condition. Therefore, we undertook a deep phenotyping discovery proteomic profiling (nano-2D-LC-QTOF MSe) on...