hrp0098fc10.1 | Multisystem Endocrine Disorders | ESPE2024

Genetic screening and tumour surveillance program outcomes in rare paediatric hereditary endocrine tumour syndromes

Oprea Alina , Izatt Louise , Ajzensztejn Michal , Snow Emma , Carroll Paul , Wei Christina

Background: Hereditary syndromic endocrine tumours are associated with significant morbidity in the paediatric population. Advances in molecular genetics enable early cascade genetic testing with early initiation of tumour screening. Controversy exists around the start age and burdens arising from screening-related harms.Objective: To describe the efficiency of the screening program for paediatric patients with genetic r...