ESPE Abstracts

ESPE Abstracts

Published by BioScientifica

hrp0097fc8.4 | Fat, metabolism and obesity 2 | ESPE2023

Irs1 expression in peripheral blood associates with obesity and cardiovascular risk parameters in school-age girls

Gómez-Vilarrubla Ariadna , Niubó-Pallàs Maria , Mas-Parés Berta , Carreras-Badosa Gemma , Bonmatí Alexandra , Estevez-Reinares Enrique , Martinez-Calcerrada Jose-María , de Zegher Francis , Ibañez Lourdes , López-Bermejo Abel , Bassols Judit

Background and Aim: IRS1 (Insulin Receptor Substrate 1) is involved in the insulin signalling pathway and abnormalities thereof have been related to metabolic disorders and obesity. In obese subjects, insulin resistance has been associated with changes in IRS1 expression in peripheral in blood. Sex-based differences in cardiovascular disease are well established. Previous results from our group disclosed the association between IRS1 placental methylation with ...

Published by BioScientifica

ESPE Abstracts

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