hrp0095fc2.5 | Bone, Growth Plate and Mineral Metabolism | ESPE2022
Ewert Annika
, Rehberg Mirko
, Hiort Olaf
, Binder Gerhard
, Schröder Carmen
, Jorch Norbert
, Richter-Unruh Annette
, Freiberg Clemens
, Peter Schlingmann Karl
, Haffner Dieter
, Schnabel Dirk
Introduction: Burosumab was approved for treatment of pediatric patients with X-linked hypophosphatemia (XLH). However, data on its efficacy in adolescents (age > 12 years) and in real-world settings are lacking.Material and methods: Here we assess the effects of 12 months burosumab treatment on mineral homeostasis in 77 pediatric XLH patients (50 children, 27 adolescents) enrolled in the German XLH Registry. Age and ...