hrp0095p2-300 | Thyroid | ESPE2022

Thyroid Function and Congenital Heart Defects in Children with Down Syndrome at Hasan Sadikin General Hospital, Bandung, Indonesia

Andriyani Dwi , Novina Novina , Rayani Apandi Putria , Faisal Faisal , Budi Kuswiyanto Rahmat , Endah Rahayuningsih Sri

Introduction: Down Syndrome (DS) is a genetic disorder that has a high mortality rate and a large number of comorbidities such as hypothyroidism and heart disease. Thyroid hormones have significant effects on cardiovascular. This study aims to describe thyroid function and congenital heart defects in Down Syndrome children at dr. Hasan Sadikin General Hospital.Methods: This is a cross-sectional study. The inclusion crite...

hrp0095p2-38 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Is Platinum-Based Chemotherapy resulted Hypomagnesemia in a Girl with Osteosarcoma? A Case Report

Novina Novina , Aprilianti Dea , Faisal Faisal , Melani Sari Nur , Suryawan Nur , Susanah Susi , Milanti Dewi Mia , Hawani Dewi , Solek Purboyo , Amalia Risan Nelly

Introduction: Magnesium is the second most abundant intracellular cation, and its low level causes several side effects related to hypoparathyroidism, hypocalcaemia, and vitamin D deficiency. Furthermore, some of the cases of hypomagnesemia are linked to platinum-based chemotherapy, resulting in neurotoxicity and nephrotoxicity. Dorsal root ganglion is the main target of platinum drugs, whereby its signs and symptoms can be detected months after chemotherapy. ...