hrp0084p2-429 | GH & IGF | ESPE2015

Effectiveness of Recombinant IGF1 Treatment in a Patient with Isolated GH IA Deficit Producer of Anti-GH Antibodies

Porcar Ines , Oriola Josep , Kratzsch Jurgen , Escribano Joaquin , Feliu Albert

Background: GH deficiency type IA represents the most serious form of isolated deficit GH (IDGH). ItÂ’s transmitted as an autosomal recessive pattern and in most cases there is a homozygous deletion of the GH1 gene. Good initial response to treatment is characteristic, although often could appear antibodies against recombinant GH.Case presentation: We report a case of a 5-year-old Pakistanist boy evaluated for severe growth failure (heigh <8.07 <...

hrp0098p1-44 | Fat, Metabolism and Obesity 1 | ESPE2024

Assessment of metabolomic-nutritional status and cardiovascular risk in adolescents with anorexia nervosa and low body weight

Sol Ventura Paula , Siurana Jose , Yeste Diego , Feliu Albert , Bosch Zelmira , Amigo Nuria

Introduction: There is a close relationship between cardiovascular disease and diet. While cardiometabolic risk has been demonstrated in adolescents with obesity, there is little information on the advanced lipoprotein profile (ALP) in adolescents with anorexia nervosa and low body weight.Objective: To evaluate the metabolomic-nutritional and cardiac profile in three groups of adolescents: 1. anorexia nervosa and low bod...